Joep + Great Escape

Joep Lange was a prominent doctor, scientist and activist. He was a pioneer in his academic field and ahead of his time in his drive to convert science into action. He never shied away from pointing out the real issues and worked tirelessly to address them. He had neither the time nor the patience to concern himself with political sensitivities. The patient always came first, whether it was one of his own patients in the Netherlands or someone he had never met in a country where proper care was out of reach.

In 1996 he discovered the link between serological response patterns to HIV infection and the speed at which HIV progresses, providing the rationale for the use of combination antiretroviral drugs. It was combination therapy that transformed HIV from a death sentence into a manageable chronic condition. After this discovery it dumbfounded Joep to see how little was being done for Africa, where millions of people were dying of AIDS. “Everything is there, the fact that HIV/AIDS treatment is not available in Africa, is at best lack of will mixed with stupidity. At worst it is racism. I am afraid there is a lot of the latter: apparently a life in Africa is worth less.”

He made it his mission to get people in Africa on treatment. He started clinical trials, pioneering treatment for pregnant mothers to stop transmission to their newborn children. The results were astounding. Then he partnered with the private sector: Heineken was the first to join, treating their employees in six African countries as early as 2001. This proved that it was possible and affordable to take antiretroviral treatment to Africa, and that the private sector could play an important role in this public good that we call healthcare. The success of this effort laid the foundation for what would later become the Global Fund to Fight AIDS, Tuberculosis and Malaria and the President’s Emergency Plan for AIDS Relief (PEPFAR).

As part of his mission to fight for inclusive quality healthcare, Joep founded both AIGHD and PharmAccess with the aim of achieving optimal impact through their complementary activities in research and action respectively. He pushed the envelope in the field of global health. Not only did he contribute to the way in which we fight AIDS today, he was also a trailblazer in a new approach to development aid: conducting groundbreaking research, applying innovations, setting up controversial partnerships with the private sector and testing new financing mechanisms in countries where no one thought it would be possible.

Indeed, more than once Joep showed the world that “nothing is impossible, especially if it is inevitable.”

Joep’s vision forms the DNA of the Joep Lange Institute, and we are honored to continue building on what he left behind.


The Joep lange Institute aims to demonstrate that practical barriers for access and effective care can be overcome. We believe that digital solutions are key to revolutionize access, quality and inclusiveness of health markets. We initiate and spur digital innovations by asking ourselves confronting questions and address them through advocacy, research and implementation. Our activities engage the health sector around this agenda.

Well-known experts from the policy, science or practice of global health are invited to give their view on innovation in their area of expertise and to discuss the potential they see for the future of global health. Including;

Marc Dybul, Executive Director, Global Fund to fight AIDS, Tuberculosis and Malaria

Professor Dan Ariely, Behavioural Economist, Duke University

Dr. Jim Yong Kim, President, Worldbank

The Joep Lange Chair and Fellows Program brings together experts from different backgrounds and geographies to collaborate on research that will help drive change in the field of global health. It is housed within the Global Health Department of the Amsterdam Medical Centre (University of Amsterdam). The first two Chairs are world-renowned behavioural economist Dan Ariely and the highly distinguished professor Mark Dybul, director of the Global Fund.

The Joep Lange institute secures research (through the Centre of Advanced Hindsight) and development funding for M-TIBA an innovative financing platform for healthcare in Africa. M-TIBA is an inclusive healthcare platform directly connecting patients, healthcare providers and healthcare payers (insurers, donors), and exchanges money and data between them.

The Home Based Hypertension Management Program aims to develop and test a new model of hypertension care delivery that uses mobile technology to offer home-based care. The Amsterdam Health and Technology Institute (ahti), enabled by the JLI, is developing this innovation in house.

The Joep Lange institute will work with Utrecht University and other partners to promote fundamental understanding of how mechanisms work and what the role technology can play to improve situations where public institutions do not function.

Honoring the legacy of Joep Lange, the Joep Lange institute has partnered with the HIV Research Trust, based in the UK, to provide an annual scholarship for PhD students from the developing world to study in the United Kingdom.

Link to Joep Lange Institute page
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Link to Updates page
  • May 22, 2017 Digital innovation & the science of delivery at INTEREST... Read More
  • May 9, 2017 A closer look at the first year of the Joep Lange... Read More
  • January 12, 2017 Watch Global Fund Director Mark Dybul's lecture... Read More
INTEREST 2017 – May 22, 2017

Digital innovation & the science of delivery at INTEREST 2017

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Progress Report 2016 – May 9, 2017

A closer look at the first year of the Joep Lange Institute

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‘We have already achieved the impossible, so we can achieve the impossible again’ – January 12, 2017

Watch Global Fund Director Mark Dybul's lecture here

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Behavioral economist Dan Ariely helps doctors change patient behaviors – December 22, 2016

Workshop report: what can doctors learn from behavioral economics?

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Dr. Mark Dybul to deliver next Joep Lange Institute Lecture – December 9, 2016

On 10 January 2017, Mark Dybul will be speaking in Amsterdam on the role of innovation and data in global health.

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Watch Dan Ariely Lecture: “We know what is the right thing to do, but still we don’t do it” – November 9, 2016

Watch the lecture by Dan Ariely on what health can learn from behavioral economics

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Prof. Dan Ariely: What can health learn from behavioral economics? – November 7, 2016

If there’s one field that can’t afford to ignore behavioral economics, it’s health. That's why we appointed Dan Ariely as Chair of the Joep Lange Chair and Fellows program.

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Nieuwsuur featured the Joep Lange Institute on HIV Drug Resistant children in Uganda – July 18, 2016

Last Sunday 17th of July, Nieuwsuur the Dutch news television program aired an item of the growing problem of HIV drug resistant children in Uganda.

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Dr. Jim Kim calls for next generation activists to tackle global health challenges – July 6, 2016

Earlier today, World Bank Group President Dr. Jim Yong Kim delivered a highly inspiring and activating first Joep Lange Institute Lecture

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Dr. Jim Yong Kim delivers the first Joep Lange Institute Lecture – June 30, 2016

World Bank President Dr. Jim Yong Kim to deliver
the first Joep Lange Institute Lecture

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Joep Lange Institute
Paasheuvelweg 25, Wing 5D
1105 BP Amsterdam Zuidoost
The Netherlands

Telephone +31 (0) 20 303 10 52

The Joep Lange Institute is an activist institute, inspired by the life and work of Joep Lange. We combine science, activism, and pragmatism to reach our goal: making health markets work for the poor where the system fails the people.

To achieve this goal we analyze the obstacles and failures in healthcare today, asking inconvenient questions when necessary. We come up with concrete solutions for healthcare quality, access and finance. We develop and test these on the ground, to see what works and what doesn’t. We advocate to scale those that have real impact for real people.

Over the last two decades, through the organizations Joep founded,  we’ve been pioneers in the delivery of HIV/AIDS treatment in Africa, and in working with the private sector in the public interest. We’ve set up health insurance for the poor, introduced quality standards for basic health clinics in Africa, and made loans available to them. Over time, we even became one of the largest private equity investors in African healthcare. Our emphasis on rigorous research has led to breakthroughs in treatment and delivery. Combined, our programs reach millions of people each month.

Keeping the patient at the heart of our approach, the Joep Lange Institute will work relentlessly with researchers and public and private partners. We believe technology is the way to connect those who are structurally excluded. It can reduce barriers to saving as well as paying for health, generate data to reduce risk and increase knowledge, and be a conduit for training and education. Many of these solutions for better access to care are available right now, the challenge is to get them implemented.

Joep taught us never to accept the constraints imposed by the status quo or by fear. Such hesitations are counterproductive for the people we want to serve. We make a radical choice for the facts, and a radical choice for people.

Bad healthcare not only undermines the health of individuals, it drives families and communities into poverty. We challenge the brightest minds and thought leaders to be part of a strategic agenda to make health markets work for the poor.


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